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CS-W001157 4
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(4S,4'S)-2,2'-(1-phenylpropane-2,2-diyl)bis(4-benzyl-4,5-dihydrooxazole)

  • CAS No. 1615699-79-0

  • Cat. No. CS-0145080
  • Purity≥95%
  • MDL No.None
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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

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*For research and further manufacturing use only, not for direct human use.

(4S,4'S)-2,2'-(1-phenylpropane-2,2-diyl)bis(4-benzyl-4,5-dihydrooxazole)|CS-0145080

Structure of 1615699-79-0

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Description

This chiral bisoxazole features a rigid 1-phenylpropane-2,2-diyl linker that enforces spatial control over its two 4-benzyl-4,5-dihydrooxazole units. The stereochemistry at the 4 and 4' positions enables precise molecular recognition, while the benzyl groups provide steric shielding and enhanced solubility. This structure supports applications in asymmetric synthesis and ligand design, where defined three-dimensional architecture is critical.

Application

(4S,4'S)-2,2'-(1-phenylpropane-2,2-diyl)bis(4-benzyl-4,5-dihydrooxazole) serves as a chiral bis-oxazoline scaffold with enhanced steric and electronic modulation, enabling efficient coordination in asymmetric catalysis. Its bench-stable, crystalline nature facilitates straightforward handling and purification. The orthogonally protected dihydrooxazole framework exhibits excellent functional group tolerance and serves as a robust building block for the synthesis of complex heterocyclic systems and catalyst precursors in medicinal chemistry workflows.

General Information

  • CAS No. 1615699-79-0
  • Cat. No. CS-0145080
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₉H₃₀N₂O₂
  • Molecular Weight 438.56
  • Synonym(s) (4S,4'S)-2,2'-(1-Phenyl-2,2-propanediyl)bis(4-benzyl-4,5-dihydro-1,3-oxazole)
  • SMILES CC(C1=N[C@@H](CC2=CC=CC=C2)CO1)(CC3=CC=CC=C3)C4=N[C@@H](CC5=CC=CC=C5)CO4

Computational Chemistry Data

  • TPSA   43.18
  • LogP   5.3154
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   8

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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