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Structure of 161957-57-9
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1-(2-Chloro-3-fluorophenyl)ethanone features a fluorinated aromatic ring with orthogonal halogen substituents, enabling precise electronic tuning. This ketone integrates readily into Suzuki-Miyaura coupling workflows and serves as a key intermediate in pharmaceutical synthesis, where its stability under standard conditions supports reliable functionalization.
1-(2-Chloro-3-fluorophenyl)ethanone serves as a versatile building block in medicinal chemistry, enabling efficient construction of biologically active heterocycles and aryl-substituted ketones. Its ortho-halogenated phenyl moiety facilitates palladium-catalyzed cross-coupling reactions and provides enhanced metabolic stability. The ketone functionality supports nucleophilic additions and condensation reactions, while the molecule exhibits excellent bench stability and compatibility with standard purification techniques.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: