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Structure of 161957-61-5
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1-(3-Bromo-2-fluorophenyl)ethanone features a brominated and fluorinated aromatic core paired with a reactive ketone group, enabling direct incorporation into Suzuki-Miyaura and Negishi coupling cascades. This bench-stable acyl moiety facilitates rapid access to complex biaryl architectures under standard conditions.
1-(3-Bromo-2-fluorophenyl)ethanone serves as a versatile building block in medicinal chemistry, enabling the construction of biologically relevant heterocyclic scaffolds via electrophilic substitution and transition-metal-catalyzed coupling reactions. The molecule's bromo and fluoro substituents offer orthogonal reactivity for sequential functionalization, while its ketone group facilitates enolization and nucleophilic addition. Bench-stable and amenable to purification by recrystallization or flash chromatography, it functions reliably in multi-step syntheses requiring high functional group tolerance.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: