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Structure of 1621-91-6
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Pyrazole-3-carboxylic acid features a rigid heterocyclic core with a carboxylic acid group at the 3-position, enabling direct conjugation in bioactive molecule design. The electron-deficient pyrazole ring facilitates hydrogen bonding and dipole interactions, enhancing target affinity in medicinal chemistry applications. This bench-stable derivative integrates readily into scaffold-hopping strategies and serves as a key building block for kinase inhibitors and receptor modulators.
Pyrazole-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of heterocyclic scaffolds through standard amide coupling and derivatization protocols. Its carboxylic acid functionality facilitates direct conjugation with amines, while the pyrazole ring provides metabolic stability and hydrogen-bonding capacity. The compound exhibits excellent bench stability and is compatible with common purification methods, making it well-suited for high-throughput screening campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: