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Structure of 162502-53-6
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4-Chloro-1-methyl-1H-indazole is a heterocyclic compound featuring a chlorine substituent at the 4-position and a methyl group at the 1-position of the indazole core. This electron-deficient scaffold integrates readily into bioactive molecule design, offering enhanced metabolic stability and favorable binding interactions in medicinal chemistry applications.
4-Chloro-1-methyl-1H-indazole serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient late-stage functionalization via palladium-catalyzed cross-coupling reactions. Its chloro group facilitates Suzuki, Stille, and Negishi couplings, while the methyl-substituted indazole core provides metabolic stability and favorable pharmacokinetic properties. Bench-stable and readily purified by crystallization, it functions as a key scaffold in the synthesis of kinase inhibitors and other bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: