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Structure of 16273-37-3
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3-Chloromandelic acid features a chlorinated aromatic ring fused to a chiral benzylic alcohol moiety, offering enhanced electronic effects and metabolic stability. This configuration enables direct incorporation into pharmaceutical intermediates, particularly in the synthesis of bioactive compounds requiring precise stereochemical control and improved lipophilicity.
3-Chloromandelic acid serves as a valuable chiral building block in synthetic organic chemistry, enabling the construction of pharmaceutically relevant heterocycles and bioactive molecules. Its ortho-chlorinated benzyl side chain provides enhanced electrophilicity for downstream functionalization, while the carboxylic acid and hydroxyl groups offer orthogonal handles for derivatization. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for use in medicinal chemistry campaigns and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P302+P352-P304+P340
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Lot numbers can be found on the outside label of a product: