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Structure of 1627722-90-0
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Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline-8-carboxylate features a boronate ester group conjugated to a quinoline scaffold, enabling efficient cross-coupling in palladium-catalyzed reactions. This bench-stable reagent integrates seamlessly into diversification workflows, delivering precise functionalization at the quinoline C5 position with minimal purification overhead.
Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline-8-carboxylate serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The tetramethylboronate group enables stable, bench-friendly handling and high functional group tolerance. It facilitates efficient C–C bond formation with aryl, heteroaryl, and vinyl halides, enabling rapid access to complex quinoline-based scaffolds relevant in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: