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Structure of 1628184-28-0
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5-Fluoro-4-methyl-2-nitropyridine features a trifunctional pyridine core with electron-withdrawing nitro and fluoro groups paired with an activating methyl substituent. This combination enables selective C–H functionalization and facilitates coupling reactions in medicinal chemistry, particularly for constructing bioactive heterocycles under mild conditions.
5-Fluoro-4-methyl-2-nitropyridine serves as a versatile building block in medicinal chemistry, enabling efficient late-stage functionalization via nucleophilic aromatic substitution. The electron-deficient pyridine ring facilitates regioselective displacement of the fluorine atom, while the nitro and methyl groups offer orthogonal handles for further derivatization. Its bench-stable crystalline form simplifies handling and purification, making it well-suited for modular synthesis of heterocyclic scaffolds and API intermediates.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: