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CS-W001157 4
Total: USD 88.00

cis-1-(tert-Butoxycarbonyl)-3-fluoropiperidine-4-carboxylic acid

  • CAS No. 1628475-90-0

  • Cat. No. CS-0049757
  • Purity≥97%
  • MDL No.MFCD28016232
  • HazMat Fee +

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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

cis-1-(tert-Butoxycarbonyl)-3-fluoropiperidine-4-carboxylic acid|CS-0049757

Structure of 1628475-90-0

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Description

This fluorinated piperidine derivative features a bench-stable tert-butyl carbamate protecting group and a strategically positioned fluorine atom, enabling selective functionalization in complex molecule synthesis. The carboxylic acid moiety supports direct coupling reactions, while the cis-configuration ensures defined stereochemical control for use in medicinal chemistry and peptide mimetic design.

Application

cis-1-(tert-Butoxycarbonyl)-3-fluoropiperidine-4-carboxylic acid serves as a versatile, bench-stable building block for the synthesis of fluorinated piperidine scaffolds. Its defined stereochemistry and orthogonal protection enable reliable incorporation into complex molecules, facilitating functional group transformations and coupling reactions in medicinal chemistry workflows. The tert-butyl carbamate group provides excellent stability and ease of removal under mild acidic conditions, while the carboxylic acid functionality supports direct derivatization or peptide coupling.

General Information

  • CAS No. 1628475-90-0
  • Cat. No. CS-0049757
  • Purity ≥97%
  • MDL No. MFCD28016232
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₈FNO₄
  • Molecular Weight 247.27
  • Synonym(s) None
  • SMILES C(OC(C)(C)C)(=O)N1C[C@H](F)[C@H](C(O)=O)CC1

Computational Chemistry Data

  • TPSA   66.84
  • LogP   2.3022
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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