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Structure of 1633-83-6
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The side-chain Mtt group can be selectively removed with 1% TFA in DCM [1,2,3] or DCM/HFIP/TFE/TES (6.5:2:1:0.5) [4], making this an excellent derivative for the synthesis by Fmoc SPPS of branched peptides and peptides modified at the Dab side-chain [4,5], and for the construction of templates and multifunctionalized resins for combinatorial synthesis. Associated Protocols and Technical ArticlesCleavage and Deprotection Protocols for Fmoc SPPSLiterature references[1] K. Barlos, et al., C. H. Schneider & A. N. Eberle (Eds), ESCOM, Leiden, 1993, pp. 283. [2] A. Aletras, et al. (1995) Int. J. Peptide Protein Res., 45, 488. [3] L. Bourel, et al. (2000) J. Peptide Sci., 6, 264. [4] K. Barlos, personal communication. [5] P. Hoogerhout, et al. (1999) J. Peptide Res., 54, 436. [6] C. Park & K. Burgess (2001) J. Comb. Chem., 3, 257.
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GHS Pictogram :
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GHS No : GHS07,GHS08
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H317-H319-H335-H351
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Precautionary Statements : P261-P264-P270-P271-P272-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: