Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

8-Bromo-2-chloroquinoline

  • CAS No. 163485-86-7

  • Cat. No. CS-W005368
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

8-Bromo-2-chloroquinoline|CS-W005368

Structure of 163485-86-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 163485-86-7
  • Cat. No. CS-W005368
  • Purity ≥96%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₅BrClN
  • Molecular Weight 242.50
  • Synonym(s) quinoline, 8-bromo-2-chloro-
  • SMILES ClC1=NC2=C(Br)C=CC=C2C=C1

Description

8-Bromo-2-chloroquinoline is a halogenated quinoline derivative featuring strategically positioned bromine and chlorine substituents. This electron-deficient scaffold enables direct functionalization in cross-coupling reactions and serves as a robust building block for pharmaceutical intermediates and ligand development.

Application

8-Bromo-2-chloroquinoline serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its dual halogenation pattern enables palladium-catalyzed cross-coupling reactions with broad functional group tolerance, facilitating the construction of complex quinoline-based scaffolds. The compound exhibits excellent bench stability and ease of purification, making it well-suited for iterative synthesis workflows and scale-up applications in API development.

Synthesis

  • Route1

    References

    • Cottet, Fabrice; Marull, Marc; Lefebvre, Olivier; Schlosser, Manfred European Journal of Organic Chemistry, 2003 , # 8 p. 1559 - 1568
  • Route2
    • null|null
      615-36-1
    • ~%
    • In-stock
      8-Bromo-2-chloroquinoline|CS-W005368
      163485-86-7

    References

    • European Journal of Organic Chemistry, , # 8 p. 1559 - 1568
  • Route3
    • N-(2-Bromophenyl)cinnamamide|CS-0162811
      71910-51-5
    • ~%
    • In-stock
      8-Bromo-2-chloroquinoline|CS-W005368
      163485-86-7

    References

    • European Journal of Organic Chemistry, , # 8 p. 1559 - 1568

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H318
Precautionary Statements : P280

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   12.89
  • LogP   3.6507
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 8-Bromo-2-chloroquinoline sigma8-Bromo-2-chloroquinoline manufacturer8-Bromo-2-chloroquinoline price8-Bromo-2-chloroquinoline structure8-Bromo-2-chloroquinoline SDSbuy 8-Bromo-2-chloroquinoline8-Bromo-2-chloroquinoline supplier8-Bromo-2-chloroquinoline uses8-Bromo-2-chloroquinoline molecular weightprice of 8-Bromo-2-chloroquinoline8-Bromo-2-chloroquinoline chemical name formula of 8-Bromo-2-chloroquinoline
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label