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CS-W001157 4
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2-(tert-Butyl)benzaldehyde

  • CAS No. 16358-79-5

  • Cat. No. CS-0128184
  • Molecule weight162.23
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(tert-Butyl)benzaldehyde|CS-0128184

Structure of 16358-79-5

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General Information

  • CAS No. 16358-79-5
  • Cat. No. CS-0128184
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₄O
  • Molecular Weight 162.23
  • Synonym(s) 2-Tert-butylbenzaldehyde
  • SMILES O=CC1=CC=CC=C1C(C)(C)C

Description

2-(tert-Butyl)benzaldehyde features a sterically hindered tert-butyl group that enhances stability and reduces unwanted side reactions. This electron-donating substituent modulates the aldehyde’s reactivity, enabling selective transformations in synthetic routes. The compound serves as a key building block in pharmaceutical intermediates and functional materials due to its robustness under standard conditions.

Application

2-(tert-Butyl)benzaldehyde serves as a valuable building block in synthetic organic chemistry, offering enhanced steric bulk and improved solubility compared to unsubstituted benzaldehydes. The tert-butyl group imparts excellent bench stability and facilitates purification, while the aldehyde function enables reliable participation in standard transformations including nucleophilic additions, Wittig reactions, and condensation processes. Its utility is well-documented in the synthesis of pharmaceutical intermediates and functionalized aromatic scaffolds.

Safety Information

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GHS Pictogram :
GHS No : GHS07,GHS08,GHS09
Signal Word : Danger
UN#: 3082
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H317-H360-H410
Precautionary Statements : P261-P264-P270-P272-P273-P280-P302+P352-P330-P362+P364-P391-P405-P501

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.7966
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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