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Structure of 1638761-56-4
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5-Bromo-7-methyl-7H-pyrrolo[2,3-d]pyrimidine features a brominated pyrrolopyrimidine core with a methyl group at the 7-position, delivering enhanced reactivity in cross-coupling transformations. The electron-deficient heterocycle integrates readily into pharmaceutical scaffolds, while the bench-stable structure enables reliable handling under standard conditions.
5-Bromo-7-methyl-7H-pyrrolo[2,3-d]pyrimidine serves as a versatile building block for purine-based heterocycles, enabling efficient Suzuki-Miyaura and Buchwald-Hartwig couplings. The bromo group facilitates palladium-catalyzed cross-coupling reactions, while the methyl substituent enhances solubility and stability. This scaffold is well-suited for medicinal chemistry campaigns targeting kinase inhibitors and nucleoside analogs, offering predictable reactivity and straightforward purification.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: