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CS-W001157 4
Total: USD 88.00

(Iodomethyl)cyclobutane

  • CAS No. 16408-62-1

  • Cat. No. CS-0053096
  • Purity≥98%
  • MDL No.MFCD06410737

*For research and further manufacturing use only, not for direct human use.

(Iodomethyl)cyclobutane|CS-0053096

Structure of 16408-62-1

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General Information

  • CAS No. 16408-62-1
  • Cat. No. CS-0053096
  • Purity ≥98%
  • MDL No. MFCD06410737
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₉I
  • Molecular Weight 196.03
  • Synonym(s) Cyclobutylmethyl Iodide
  • SMILES ICC1CCC1

Description

(Iodomethyl)cyclobutane is a strained, halogenated cycloalkane featuring a reactive iodomethyl group tethered to a cyclobutane ring. This configuration enables efficient functionalization in synthetic transformations, particularly in cross-coupling reactions and C–C bond formation under mild conditions. The compound exhibits high reactivity due to ring strain and the electrophilic nature of the iodide, facilitating rapid incorporation into complex molecular architectures.

Application

(Iodomethyl)cyclobutane serves as a versatile alkylating agent in synthetic organic chemistry, enabling efficient introduction of the cyclobutylmethyl group into diverse substrates. Its iodide functionality facilitates smooth displacement reactions with nucleophiles under mild conditions, offering high reactivity and compatibility with various functional groups. The molecule exhibits good bench stability and is readily purified by distillation or column chromatography, making it well-suited for use in medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS06,GHS08
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331-H341
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   2.2215
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   1

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