2-Methylquinolin-7-ol

Name: 2-Methylquinolin-7-ol
Brand: ChemScene
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CAS No. 165112-03-8
Cat. No. CS-0188499
Purity≥97%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 165112-03-8

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Description

2-Methylquinolin-7-ol features a fused quinoline core with a methyl group at the 2-position and a phenolic hydroxyl at the 7-position, delivering enhanced solubility and stability. This scaffold enables direct incorporation into bioactive molecules, particularly in kinase inhibitors and fluorescent probes. The electron-rich aromatic system facilitates efficient metal coordination and π–π interactions.

Application

2-Methylquinolin-7-ol serves as a versatile building block in medicinal chemistry, enabling efficient access to quinoline-based scaffolds through standard functionalization reactions. Its phenolic hydroxyl group offers reliable derivatization potential, while the methyl substituent enhances metabolic stability and modulates electronic properties. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns targeting kinase inhibitors and other bioactive heterocycles.

General Information

CAS No. 165112-03-8
Cat. No. CS-0188499
Purity ≥97%
MDL No. None
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₉NO
Molecular Weight 159.18
Synonym(s) 7-Quinolinol, 2-methyl-
SMILES CC1=NC2=C(C=C1)C=CC(=C2)O

Computational Chemistry Data

TPSA 33.12
LogP 2.24882
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds quinoline compounds

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2-Methylquinolin-7-ol

CAS No. 165112-03-8

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