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Structure of 1657030-28-8
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This pyrrolidine derivative features a tert-butoxycarbonyl-protected amine and a methyl group at the 5-position, enabling direct incorporation into peptide chains. The stereochemistry at C2 and C5 ensures predictable conformational control in synthetic intermediates. Bench-stable under standard conditions, it facilitates efficient coupling reactions without racemization.
(2R,5R)-1-(tert-Butoxycarbonyl)-5-methylpyrrolidine-2-carboxylic acid serves as a stereochemically defined building block for the synthesis of bioactive pyrrolidine-containing scaffolds. The Boc group enables straightforward protection and deprotection under mild acidic conditions, while the C5 methyl substituent provides steric and electronic modulation. This derivative exhibits excellent bench stability and facilitates efficient coupling reactions, making it well-suited for peptide and medicinal chemistry applications requiring controlled stereochemistry and functional group compatibility.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: