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Structure of 166023-21-8
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Intercalating into lipid bilayers, DC-Cholesterol HCl (CAS 166023-21-8) enhances cationic liposome-mediated nucleic acid delivery efficiency in mammalian cell transfection assays.
DC-Cholesterol HCl (CAS 166023-21-8) forms stable, cationic liposomes with L-α-phosphatidylethanolamine, dioleoyl, enabling efficient cytoplasmic delivery of nucleic acids across diverse mammalian cell lines through enhanced membrane fusion and endosomal escape. This setup streamlines gene delivery. Researchers leverage this for high-transfection efficiency in hard-to-transfect primary cells and stem cell systems.
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Hazard Statements : H413
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Precautionary Statements : P273-P501
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Lot numbers can be found on the outside label of a product: