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Structure of 166312-49-8
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2-Methoxy-4-(trifluoromethoxy)phenol features a phenolic hydroxyl group flanked by electron-withdrawing trifluoromethoxy and electron-donating methoxy substituents, creating a uniquely polarized aromatic system. This structural arrangement enhances its utility in synthetic routes requiring controlled reactivity, particularly in the development of bioactive molecules and advanced materials.
2-Methoxy-4-(trifluoromethoxy)phenol serves as a valuable building block in the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-methoxy and para-trifluoromethoxy substituents confer enhanced metabolic stability and lipophilicity, while the phenolic hydroxyl group enables facile derivatization via etherification, esterification, or coupling reactions. The compound exhibits good bench stability and is compatible with standard synthetic protocols, facilitating its use in medicinal chemistry campaigns targeting CNS agents and kinase inhibitors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: