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CS-W001157 4
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2-(Bromomethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

  • CAS No. 166330-03-6

  • Cat. No. CS-0040849
  • Molecule weight220.90
  • Purity≥95%
  • MDL No.MFCD09271779

*For research and further manufacturing use only, not for direct human use.

2-(Bromomethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0040849

Structure of 166330-03-6

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General Information

  • CAS No. 166330-03-6
  • Cat. No. CS-0040849
  • Purity ≥95%
  • MDL No. MFCD09271779
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₄BBrO₂
  • Molecular Weight 220.90
  • Synonym(s) Bromomethylboronic acid, pinacol ester
  • SMILES CC1(C)C(C)(C)OB(CBr)O1

Description

2-(Bromomethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane delivers a reactive bromomethyl handle paired with a stable boronate ester, enabling efficient cross-coupling and functional group interconversions under mild conditions.

Synthesis

  • Route1
    • In-stock
      2,3-Dimethylbutane-2,3-diol|CS-0015356
      76-09-5
    • null|null
      74-95-3
    • ~80%
    • In-stock
      2-(Bromomethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0040849
      166330-03-6

    References

    • Pulis, Alexander P.; Aggarwal, Varinder K. Journal of the American Chemical Society, 2012 , vol. 134, # 27 p. 11298 - 11298
  • Route2

    References

    • Eisai RandD Management Co., Ltd. Patent: US2008/15351 A1, 2008 ; Location in patent: Page/Page column 11 ;
  • Route3
    • In-stock
      2,3-Dimethylbutane-2,3-diol|CS-0015356
      76-09-5
    • null|null
      5419-55-6
    • null|null
      74-95-3
    • ~70%
    • In-stock
      2-(Bromomethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0040849
      166330-03-6

    References

    • Eisai RandD Management Co., Ltd. Patent: EP2062901 A1, 2009 ; Location in patent: Page/Page column 12-13 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315-H319-H335
Precautionary Statements : P210-P264-P280-P302+P352-P362-P501

Quality Control

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Computational Chemistry Data

  • TPSA   18.46
  • LogP   2.0127
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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