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Structure of 16634-91-6
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2-Methyl-5-nitrobenzaldehyde features a nitro group at the para position relative to the aldehyde, enhancing electrophilicity for efficient coupling reactions. The methyl substituent provides steric and electronic modulation, improving solubility and stability under standard conditions. This aromatic aldehyde serves as a key building block in synthesizing functional dyes, pharmaceutical intermediates, and ligands.
2-Methyl-5-nitrobenzaldehyde serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted heterocycles and pharmaceutical intermediates. Its electron-deficient aromatic ring, combined with orthogonal aldehyde and nitro functionalities, facilitates diverse transformations including Mannich reactions, condensations, and transition-metal-catalyzed couplings. The compound exhibits good bench stability and is readily purified by recrystallization or column chromatography, supporting its use in multi-step synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: