3,5-Diiodo-D-tyrosine

Name: 3,5-Diiodo-D-tyrosine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 16711-71-0
Cat. No. CS-W001037
Purity≥97%
MDL No.MFCD00237693

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 16711-71-0

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Description

3,5-Diiodo-D-tyrosine features a D-configured tyrosine backbone bearing iodine substituents at the 3 and 5 positions of the aromatic ring. This electron-deficient phenolic scaffold enhances metabolic stability and serves as a key building block for radiolabeled peptides in molecular imaging. The diiodo substitution pattern enables efficient isotopic exchange and facilitates incorporation into bioactive sequences with high fidelity.

Application

3,5-Diiodo-D-tyrosine serves as a valuable building block for the synthesis of iodinated peptide scaffolds and radiolabeled biomolecules. Its D-configured backbone and ortho-diiodo substitution pattern confer enhanced metabolic stability and selective bioorthogonal reactivity, enabling efficient incorporation into therapeutic peptides via solid-phase synthesis. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for applications in radioisotope labeling and targeted drug delivery research.

General Information

CAS No. 16711-71-0
Cat. No. CS-W001037
Purity ≥97%
MDL No. MFCD00237693
Storage 4°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₉I₂NO₃
Molecular Weight 432.98
Synonym(s) None
SMILES N[C@H](CC1=CC(I)=C(O)C(I)=C1)C(O)=O

Computational Chemistry Data

TPSA 83.55
LogP 1.5558
H_Acceptors 3
H_Donors 3
Rotatable_Bonds 3

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Tyrosine and derivatives

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

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3,5-Diiodo-D-tyrosine

CAS No. 16711-71-0

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