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CS-W001157 4
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2-(Piperidin-3-yl)ethan-1-ol hydrochloride

  • CAS No. 16780-04-4

  • Cat. No. CS-D1062
  • Purity≥95%
  • MDL No.MFCD14583117
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-(Piperidin-3-yl)ethan-1-ol hydrochloride|CS-D1062

Structure of 16780-04-4

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Description

This piperidinyl-ethyl alcohol hydrochloride features a tertiary amine scaffold with a pendant hydroxyl group, enabling dual hydrogen-bonding capacity and enhanced solubility. The protonated piperidine ring improves aqueous compatibility while maintaining metabolic stability. This bifunctional moiety integrates efficiently into bioactive scaffolds for medicinal chemistry applications.

Application

2-(Piperidin-3-yl)ethan-1-ol hydrochloride serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard amine functionalization and cyclization protocols. The piperidine core offers favorable solubility and metabolic stability, while the primary alcohol facilitates derivatization via esterification or ether formation. Bench-stable and readily purified by recrystallization, it functions effectively in multistep synthesis workflows requiring moderate basicity and controlled reactivity.

General Information

  • CAS No. 16780-04-4
  • Cat. No. CS-D1062
  • Purity ≥95%
  • MDL No. MFCD14583117
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₆ClNO
  • Molecular Weight 165.66
  • Synonym(s) 2-(3-Piperidyl)ethanol hydrochloride
  • SMILES OCCC1CNCCC1.Cl

Computational Chemistry Data

  • TPSA   32.26
  • LogP   0.7902
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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