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Structure of 16859-59-9
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3-Hydroxyisobenzofuran-1(3H)-one features a fused bicyclic core with a phenolic hydroxyl and lactone functionality, offering enhanced stability and polarity for use in synthetic intermediates. This scaffold integrates readily into bioactive molecule frameworks due to its defined stereochemical environment and compatibility with diverse coupling reactions under standard conditions.
3-Hydroxyisobenzofuran-1(3H)-one serves as a versatile scaffold for the synthesis of bioactive heterocycles and natural product analogs. Its ortho-hydroxylated lactone functionality enables facile derivatization via esterification, oxidation, or metal-catalyzed coupling reactions. Bench-stable and compatible with common protecting group strategies, it functions as a reliable building block in medicinal chemistry campaigns targeting kinase inhibitors and anti-inflammatory agents.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: