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Structure of 168618-44-8
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2′-Methyl[1,1′-biphenyl]-3-carboxylic acid features a sterically hindered biphenyl scaffold with a methyl group at the 2′-position and a carboxylic acid at the 3-position, delivering enhanced solubility and metabolic stability. This configuration enables efficient coupling in transition metal-catalyzed reactions and supports the construction of complex biaryl architectures in medicinal chemistry and materials science.
2′-Methyl[1,1′-biphenyl]-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of biaryl scaffolds with defined steric and electronic properties. The carboxylic acid functionality facilitates direct coupling reactions, while the methyl group at the 2′-position provides moderate steric hindrance and enhances metabolic stability. This compound exhibits good bench stability and functional group tolerance, making it suitable for iterative synthesis workflows and scale-up applications in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P301+P310-P302+P352-P304+P341-P330-P363-P501
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Lot numbers can be found on the outside label of a product: