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Structure of 169339-41-7
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Methyl 2-(3-fluoro-4-nitrophenyl)acetate features a fluorinated aryl ring paired with a nitro group, enabling strong electron-withdrawing effects that enhance reactivity in cross-coupling and nucleophilic substitution processes. The ester functionality provides solubility in common organic solvents and facilitates downstream derivatization under standard conditions.
Methyl 2-(3-fluoro-4-nitrophenyl)acetate serves as a versatile building block for nitroaryl-containing heterocycles and pharmaceutical intermediates. The ortho-fluoro and para-nitro groups enable sequential functionalization via palladium-catalyzed cross-coupling and in situ reduction, while the ester moiety supports hydrolysis or nucleophilic substitution. Bench-stable and compatible with standard synthetic workflows, it facilitates efficient access to bioactive scaffolds in medicinal chemistry.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: