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Structure of 169685-29-4
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4-(Trifluoromethoxy)benzenethiol features a trifluoromethoxy group that imparts enhanced electron-withdrawal and metabolic stability, while the thiol moiety enables robust conjugation chemistry. This combination delivers high reactivity in bioconjugation and materials functionalization under ambient conditions.
4-(Trifluoromethoxy)benzenethiol serves as a valuable building block in medicinal chemistry and materials science, enabling the synthesis of functionalized arylthio derivatives. Its trifluoromethoxy group imparts enhanced metabolic stability and lipophilicity, while the thiol functionality facilitates coupling reactions via gold catalysis or oxidative S–S bond formation. The compound exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for iterative synthetic workflows.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301+H311+H331-H315-H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: