5-bromo-3-chloro-8-methoxyisoquinoline

Name: 5-bromo-3-chloro-8-methoxyisoquinoline
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1696988-00-7
Cat. No. CS-0031822
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-bromo-3-chloro-8-methoxyisoquinoline|CS-0031822

Structure of 1696988-00-7

Size

Price

Quantity

* Please select Quantity before adding items.

Description

5-Bromo-3-chloro-8-methoxyisoquinoline features a halogenated isoquinoline core with strategically positioned bromo, chloro, and methoxy substituents. This electron-deficient scaffold enables efficient coupling in cross-coupling reactions, particularly in Pd-catalyzed transformations. The methoxy group enhances solubility and modulates reactivity, while the ortho-halogen pattern supports sequential functionalization. Bench-stable and moisture-tolerant, it serves as a robust building block for medicinal chemistry and materials science applications.

Application

5-Bromo-3-chloro-8-methoxyisoquinoline serves as a versatile building block in medicinal chemistry and catalytic cross-coupling reactions. The bromo group enables palladium-catalyzed coupling with boronic acids, stannanes, or amines, while the chloro substituent offers orthogonal reactivity for sequential functionalization. The methoxy group enhances solubility and modulates electronic properties. This compound exhibits excellent bench stability and is compatible with standard purification methods, facilitating efficient synthesis of complex isoquinoline-based scaffolds.

General Information

CAS No. 1696988-00-7
Cat. No. CS-0031822
Purity ≥98%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₇BrClNO
Molecular Weight 272.53
Synonym(s) None
SMILES COC1=CC=C(Br)C2=C1C=NC(Cl)=C2

Computational Chemistry Data

TPSA 22.12
LogP 3.6593
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Isoquinoline compounds

Key Words

5-bromo-3-chloro-8-methoxyisoquinoline sigma5-bromo-3-chloro-8-methoxyisoquinoline manufacturer5-bromo-3-chloro-8-methoxyisoquinoline price5-bromo-3-chloro-8-methoxyisoquinoline structure5-bromo-3-chloro-8-methoxyisoquinoline SDSbuy 5-bromo-3-chloro-8-methoxyisoquinoline5-bromo-3-chloro-8-methoxyisoquinoline supplier5-bromo-3-chloro-8-methoxyisoquinoline uses5-bromo-3-chloro-8-methoxyisoquinoline molecular weightprice of 5-bromo-3-chloro-8-methoxyisoquinoline5-bromo-3-chloro-8-methoxyisoquinoline chemical name formula of 5-bromo-3-chloro-8-methoxyisoquinoline

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

5-bromo-3-chloro-8-methoxyisoquinoline

CAS No. 1696988-00-7

Recommended Products