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Structure of 169751-73-9
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Tos-PEG4-CH2-Boc features a hydrophilic PEG4 spacer flanked by a tosyl (Tos) group and a Boc-protected amine, enabling orthogonal functionalization. This bifunctional reagent facilitates selective conjugation in aqueous environments while maintaining stability under standard bench conditions.
Tos-PEG4-CH2-Boc serves as a versatile bifunctional building block for peptide and oligonucleotide synthesis, enabling efficient conjugation strategies. The tosyl (Tos) group provides a reliable leaving group for nucleophilic substitution, while the PEG4 spacer offers enhanced solubility and reduced aggregation. The CH2-Boc moiety allows for mild acid-labile deprotection, facilitating sequential functionalization. This compound exhibits excellent bench stability, compatibility with diverse reaction conditions, and straightforward purification by standard chromatographic methods.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: