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Structure of 1698908-91-6
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This boronate ester features a difluoromethyl-substituted aryl group, enhancing electron deficiency and metabolic stability. The tetramethyl-dioxaborolane moiety enables robust coupling in Suzuki-Miyaura reactions under standard conditions. Bench-stable and moisture-tolerant, it streamlines the synthesis of complex fluorinated biaryl scaffolds in medicinal chemistry workflows.
This boronate ester serves as a robust coupling partner in palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl scaffolds. The difluoromethyl and ortho-fluoro substituents enhance metabolic stability and modulate electronic properties, while the tetramethyl-substituted dioxaborolane ring ensures excellent bench stability and compatibility with diverse reaction conditions. Ideal for medicinal chemistry applications requiring fluorinated aromatic motifs.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H315-H318-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: