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CS-W001157 4
Total: USD 88.00

4-Bromo-2,5-dimethylpyridine

  • CAS No. 17117-23-6

  • Cat. No. CS-W022092
  • Purity≥95%
  • MDL No.MFCD00234307

*For research and further manufacturing use only, not for direct human use.

4-Bromo-2,5-dimethylpyridine|CS-W022092

Structure of 17117-23-6

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General Information

  • CAS No. 17117-23-6
  • Cat. No. CS-W022092
  • Purity ≥95%
  • MDL No. MFCD00234307
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈BrN
  • Molecular Weight 186.05
  • Synonym(s) None
  • SMILES CC1=CN=C(C)C=C1Br

Description

4-Bromo-2,5-dimethylpyridine features a sterically hindered pyridine core with complementary electron-rich methyl groups and a reactive bromine at the 4-position. This combination enables efficient cross-coupling transformations under mild conditions, delivering functionalized heterocycles with high regiocontrol. The molecule exhibits excellent bench stability and solubility in common organic solvents, facilitating seamless integration into synthetic workflows.

Application

4-Bromo-2,5-dimethylpyridine serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions due to its stable bromide functionality and electron-rich pyridine core. The methyl groups at the 2- and 5-positions enhance regioselectivity and provide steric control in downstream transformations. Its bench-stable nature and compatibility with standard synthetic protocols make it ideal for constructing complex heterocyclic scaffolds and functionalized aryl derivatives.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.46094
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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