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Structure of 173194-95-1
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6-Hydroxynaphthalene-2-boronic acid delivers a strategically positioned boronic acid group adjacent to a phenolic hydroxyl, enabling efficient coupling in Suzuki-Miyaura reactions. The hydroxyl enhances solubility and stabilizes the boronate moiety under physiological conditions. This dual-functional architecture supports robust cross-coupling with aryl halides and facilitates incorporation into bioactive scaffolds.
6-Hydroxynaphthalene-2-boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds. Its hydroxyl group provides orthogonal reactivity for selective functionalization, while the boronic acid moiety offers excellent stability and compatibility with diverse reaction conditions. Ideal for medicinal chemistry and materials synthesis, it facilitates straightforward purification and demonstrates broad functional group tolerance in standard coupling protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: