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Structure of 17322-91-7
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1H-Pyrrolo[3,2-b]pyridin-5(4H)-one is a heterocyclic scaffold featuring a fused pyrrole-pyridine core with a lactam functionality. This electron-deficient system enables direct incorporation into bioactive molecules, offering enhanced metabolic stability and favorable binding interactions in medicinal chemistry applications.
1H-Pyrrolo[3,2-b]pyridin-5(4H)-one serves as a versatile heterocyclic building block in medicinal chemistry, enabling the synthesis of kinase inhibitors and other bioactive scaffolds. Its fused tricyclic structure exhibits good bench stability and functional group tolerance, facilitating downstream derivatization via nucleophilic substitution or palladium-catalyzed coupling. The molecule functions as a key intermediate in the development of targeted therapeutics, particularly where planar aromatic systems with hydrogen-bonding capacity are required.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: