(R)-4-Benzhydryloxazolidin-2-one

Name: (R)-4-Benzhydryloxazolidin-2-one
Brand: ChemScene
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CAS No. 173604-33-6
Cat. No. CS-0132494
Purity≥97%
MDL No.MFCD01863565

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-4-Benzhydryloxazolidin-2-one|CS-0132494

Structure of 173604-33-6

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Description

(R)-4-Benzhydryloxazolidin-2-one is a chiral oxazolidinone scaffold featuring a rigid benzhydryl group that enhances stereochemical stability. This configuration enables selective asymmetric synthesis, particularly in enantioselective catalysis and peptide bond formation. The molecule integrates readily into complex molecular architectures due to its defined stereochemistry and compatibility with diverse reaction conditions.

Application

(R)-4-Benzhydryloxazolidin-2-one serves as a robust chiral auxiliary in asymmetric synthesis, enabling stereoselective transformations through its well-defined C2 stereocenter. The oxazolidinone ring exhibits excellent bench stability and facilitates efficient enolization and nucleophilic addition reactions. Its benzhydryl group enhances solubility and simplifies purification, while the carbonyl functionality supports diverse functionalization pathways, making it a reliable building block for complex molecular architectures in medicinal chemistry and process development.

General Information

CAS No. 173604-33-6
Cat. No. CS-0132494
Purity ≥97%
MDL No. MFCD01863565
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₆H₁₅NO₂
Molecular Weight 253.30
Synonym(s) (R)-(+)-4-(Diphenylmethyl)-2-oxazolidinone
SMILES O=C1OC[C@@H](C(C2=CC=CC=C2)C3=CC=CC=C3)N1

Computational Chemistry Data

TPSA 38.33
LogP 2.9269
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 3

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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(R)-4-Benzhydryloxazolidin-2-one

CAS No. 173604-33-6

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