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CS-W001157 4
Total: USD 88.00

1-[4-(Trifluoromethyl)phenyl]ethanol

  • CAS No. 1737-26-4

  • Cat. No. CS-0067774
  • Purity≥97%
  • MDL No.MFCD00039618
  • HazMat Fee +

    HazMat Fee

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-[4-(Trifluoromethyl)phenyl]ethanol|CS-0067774

Structure of 1737-26-4

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Description

1-[4-(Trifluoromethyl)phenyl]ethanol features a trifluoromethyl-substituted aryl ring paired with a benzylic alcohol functionality, enabling direct integration into pharmaceutical intermediates and functional materials. The electron-withdrawing trifluoromethyl group enhances metabolic stability while the hydroxyl moiety offers a handle for derivatization under standard conditions. This bench-stable compound serves as a key building block in synthetic routes requiring aromatic alcohols with tuned electronic properties.

Application

1-[4-(Trifluoromethyl)phenyl]ethanol serves as a versatile building block in medicinal chemistry, enabling the synthesis of biologically active aryl-alkanol scaffolds. Its trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, while the secondary alcohol facilitates straightforward derivatization via oxidation, protection, or coupling reactions. The compound exhibits good bench stability and is readily purified by distillation or chromatography, making it well-suited for scalable synthesis and process development.

General Information

  • CAS No. 1737-26-4
  • Cat. No. CS-0067774
  • Purity ≥97%
  • MDL No. MFCD00039618
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉F₃O
  • Molecular Weight 190.16
  • Synonym(s) ALPHA-METHYL-4-(TRIFLUOROMETHYL) BENZYL ALCOHOL, TECH.,
  • SMILES CC(O)C1=CC=C(C(F)(F)F)C=C1

Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.7587
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P302+P352-P304+P340

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