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Structure of 1737-26-4
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1-[4-(Trifluoromethyl)phenyl]ethanol features a trifluoromethyl-substituted aryl ring paired with a benzylic alcohol functionality, enabling direct integration into pharmaceutical intermediates and functional materials. The electron-withdrawing trifluoromethyl group enhances metabolic stability while the hydroxyl moiety offers a handle for derivatization under standard conditions. This bench-stable compound serves as a key building block in synthetic routes requiring aromatic alcohols with tuned electronic properties.
1-[4-(Trifluoromethyl)phenyl]ethanol serves as a versatile building block in medicinal chemistry, enabling the synthesis of biologically active aryl-alkanol scaffolds. Its trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, while the secondary alcohol facilitates straightforward derivatization via oxidation, protection, or coupling reactions. The compound exhibits good bench stability and is readily purified by distillation or chromatography, making it well-suited for scalable synthesis and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P302+P352-P304+P340
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Lot numbers can be found on the outside label of a product: