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Structure of 174346-82-8
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tert-Butyl 2-(hydroxymethyl)azetidine-1-carboxylate delivers a strained azetidine core functionalized with a hydroxymethyl group, enabling direct incorporation into bioactive scaffolds. The tert-butyl ester provides stability and convenient deprotection under mild acidic conditions. This compound serves as a key intermediate in the synthesis of pharmacologically active molecules requiring precise stereocontrol and metabolic stability.
tert-Butyl 2-(hydroxymethyl)azetidine-1-carboxylate serves as a versatile building block in medicinal chemistry, enabling the efficient construction of azetidine-containing scaffolds. The hydroxymethyl group facilitates downstream functionalization via oxidation, protection, or coupling reactions, while the tert-butyl ester offers excellent bench stability and ease of removal under mild acidic conditions. Its compatibility with diverse reaction conditions makes it a practical choice for synthesizing bioactive molecules and peptide mimetics.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: