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CS-W001157 4
Total: USD 88.00

7-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride

  • CAS No. 1745-05-7

  • Cat. No. CS-0043245
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

7-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride|CS-0043245

Structure of 1745-05-7

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Description

7-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride is a bench-stable, moisture-tolerant heterocyclic amine featuring a methoxy group at the C7 position. This electron-rich scaffold integrates readily into medicinal chemistry campaigns, offering enhanced solubility and metabolic stability. The hydrochloride salt form ensures excellent crystallinity and handling ease in synthetic workflows.

Application

7-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride serves as a stable, bench-ready building block for the synthesis of bioactive alkaloids and pharmaceutical intermediates. Its well-defined nitrogen functionality enables straightforward functionalization in standard coupling and alkylation reactions, while the methoxy group provides predictable regioselectivity in electrophilic substitutions. The hydrochloride salt enhances solubility and handling convenience in aqueous or polar organic media, facilitating purification and integration into multi-step synthetic sequences.

General Information

  • CAS No. 1745-05-7
  • Cat. No. CS-0043245
  • Purity ≥97%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₄ClNO
  • Molecular Weight 199.68
  • Synonym(s) 7-METHOXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HYDROCHLORIDE
  • SMILES COC1=CC2=C(C=C1)CCNC2.Cl

Computational Chemistry Data

  • TPSA   21.26
  • LogP   1.7627
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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