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Structure of 17450-34-9
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Ethyl 2-(1H-imidazol-1-yl)acetate features a polar imidazole ring tethered to an ester-functionalized alkyl chain, enabling efficient incorporation into heterocyclic scaffolds. This bench-stable reagent facilitates direct coupling in transition-metal-catalyzed cross-coupling reactions and serves as a key intermediate in medicinal chemistry for accessing bioactive nitrogen-containing compounds.
Ethyl 2-(1H-imidazol-1-yl)acetate serves as a versatile building block in medicinal chemistry, enabling efficient access to imidazole-containing scaffolds via standard functional group transformations. The ester moiety facilitates derivatization through hydrolysis or nucleophilic substitution, while the pendant imidazole ring provides robust hydrogen-bonding capability and metabolic stability. Bench-stable and readily purified by column chromatography, it functions reliably in coupling reactions, heterocycle synthesis, and peptide conjugation workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: