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CS-W001157 4
Total: USD 88.00

3-(Chloromethyl)cyclobutanone

  • CAS No. 175021-13-3

  • Cat. No. CS-0054362
  • Purity≥95%
  • MDL No.None
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-(Chloromethyl)cyclobutanone|CS-0054362

Structure of 175021-13-3

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Description

3-(Chloromethyl)cyclobutanone is a reactive cyclobutanone derivative featuring a chloromethyl group that enables efficient functionalization. This electrophilic handle facilitates nucleophilic substitution and conjugate addition reactions, serving as a key intermediate in the synthesis of complex cyclic architectures. The strained ring system enhances reactivity while maintaining stability under standard handling conditions.

Application

3-(Chloromethyl)cyclobutanone serves as a versatile building block for the construction of functionalized cyclobutane scaffolds. The chloromethyl group enables nucleophilic substitution reactions, while the ketone functionality supports enolate chemistry and reductive transformations. Its bench-stable nature and compatibility with diverse reaction conditions facilitate efficient synthesis of complex heterocycles and medicinally relevant frameworks in organic and medicinal chemistry workflows.

General Information

  • CAS No. 175021-13-3
  • Cat. No. CS-0054362
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₇ClO
  • Molecular Weight 118.56
  • Synonym(s) 3-(chloromethyl)cyclobutan-1-one
  • SMILES O=C1CC(CCl)C1

Computational Chemistry Data

  • TPSA   17.07
  • LogP   1.2043
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H225
Precautionary Statements : P210-P243-P273-P403

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