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Structure of 17536-00-4
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3,5-Diisopropyl-1H-pyrazole features a sterically hindered pyrazole core with two bulky isopropyl groups at the 3 and 5 positions, enhancing stability and solubility in organic media. This configuration imparts resistance to decomposition under standard bench conditions, enabling reliable use in synthetic transformations requiring robust heterocyclic scaffolds.
3,5-Diisopropyl-1H-pyrazole serves as a sterically hindered pyrazole scaffold with enhanced solubility and bench stability, enabling its use in medicinal chemistry lead optimization. The diisopropyl substitution pattern provides favorable steric shielding of the nitrogen atoms, improving metabolic resistance and reducing unwanted side reactions during downstream functionalization. It functions effectively as a bioisostere for phenyl or other heterocycles in API development and facilitates efficient coupling reactions due to its moderate nucleophilicity and compatibility with standard synthetic protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: