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Structure of 175610-68-1
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1-Bromo-2-fluoro-3-methyl-5-nitrobenzene features a densely functionalized aromatic core with orthogonal reactivity. The bromo and fluoro substituents enable palladium-catalyzed cross-coupling and nucleophilic substitution, while the para-nitro group serves as a strong electron-withdrawing anchor. This combination supports precise molecular elaboration in medicinal chemistry and materials synthesis.
1-Bromo-2-fluoro-3-methyl-5-nitrobenzene serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The bromo group facilitates efficient Suzuki, Stille, or Negishi coupling, while the fluoro and nitro substituents offer directed functionalization potential. Its bench-stable nature and compatibility with diverse reaction conditions make it well-suited for multi-step synthesis of complex aromatic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: