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CS-W001157 4
Total: USD 88.00

3-Nitroquinoline

  • CAS No. 17576-53-3

  • Cat. No. CS-0155672
  • Purity≥98%
  • MDL No.MFCD00956379

*For research and further manufacturing use only, not for direct human use.

3-Nitroquinoline|CS-0155672

Structure of 17576-53-3

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General Information

  • CAS No. 17576-53-3
  • Cat. No. CS-0155672
  • Purity ≥98%
  • MDL No. MFCD00956379
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆N₂O₂
  • Molecular Weight 174.16
  • Synonym(s) Quinoline,nitro
  • SMILES C1=CC2=CC(=CN=C2C=C1)[N+](=O)[O-]

Description

3-Nitroquinoline is a heterocyclic aromatic compound featuring a nitro group at the 3-position of the quinoline scaffold. This electron-deficient framework enhances reactivity in nucleophilic substitution and transition metal-catalyzed coupling processes. The molecule exhibits good solubility in organic solvents and stability under standard bench conditions, making it a valuable intermediate for pharmaceutical synthesis and materials chemistry.

Application

3-Nitroquinoline serves as a versatile building block in medicinal chemistry, enabling the synthesis of nitrogen-containing heterocycles through well-established transformations. Its nitro group facilitates electrophilic substitution and subsequent reduction to an amino derivative, while the quinoline core provides structural rigidity and π-systems for metal coordination or bioactive interactions. The compound exhibits good bench stability and is compatible with standard purification techniques, making it suitable for iterative synthetic workflows in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   56.03
  • LogP   2.143
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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