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CS-W001157 4
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Methyl 2-pyridyl ketone oxime

  • CAS No. 1758-54-9

  • Cat. No. CS-M2152
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 2-pyridyl ketone oxime|CS-M2152

Structure of 1758-54-9

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General Information

  • CAS No. 1758-54-9
  • Cat. No. CS-M2152
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈N₂O
  • Molecular Weight 136.15
  • Synonym(s) Ethanone, 1-(2-pyridinyl)-, oxime
  • SMILES C/C(C1=NC=CC=C1)=N/O

Description

t-Boc-Aminooxy-PEG3-thiol is a crosslinker containing a t-Boc-aminooxy group and a thiol group. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, The protected aminoxy can be deprotected under mild acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.

Synthesis

  • Route1
    • 1-(Pyridin-2-yl)ethanone  Imatinib Impurity|CS-0167014
      1122-62-9
    • ~81%
    • Methyl 2-pyridyl ketone oxime|CS-M2152
      1758-54-9

    References

    • Svobodova, Eva; Cibulka, Radek; Hampl, Frantisek; Smidrkal, Jan; Liska, Frantisek Collection of Czechoslovak Chemical Communications, 2005 , vol. 70, # 4 p. 441 - 465
  • Route2

    References

    • Journal of the American Chemical Society, , vol. 130, # 52 p. 17893 - 17906
  • Route3
    • null|null
      100-69-6
    • ~58%
    • Methyl 2-pyridyl ketone oxime|CS-M2152
      1758-54-9

    References

    • Prateeptongkum, Saisuree; Jovel, Irina; Jackstell, Ralf; Vogl, Nadine; Weckbecker, Christoph; Beller, Matthias Chemical Communications, 2009 , # 15 p. 1990 - 1992

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   45.48
  • LogP   1.2798
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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