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CS-W001157 4
Total: USD 88.00

HO-PEG13-OH

  • CAS No. 17598-96-8

  • Cat. No. CS-0115026
  • Purity≥96%
  • MDL No.MFCD20926392

*For research and further manufacturing use only, not for direct human use.

HO-PEG13-OH|CS-0115026

Structure of 17598-96-8

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General Information

  • CAS No. 17598-96-8
  • Cat. No. CS-0115026
  • Purity ≥96%
  • MDL No. MFCD20926392
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₆H₅₄O₁₄
  • Molecular Weight 590.70
  • Synonym(s) None
  • SMILES OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

Description

HO-PEG13-OH is a linear, hydrophilic poly(ethylene glycol) chain bearing hydroxyl termini. This bench-stable reagent features enhanced solubility in aqueous and polar organic solvents, enabling seamless integration into conjugation workflows. The terminal hydroxyl groups facilitate straightforward derivatization for bioconjugation or surface functionalization applications.

Application

HO-PEG13-OH serves as a high-molecular-weight, hydrophilic spacer in conjugate synthesis, enabling improved solubility and pharmacokinetic properties in bioconjugates. Its linear poly(ethylene glycol) chain provides excellent stability, low non-specific binding, and facile purification due to its polar nature and resistance to metabolic degradation. Widely used in drug delivery systems, it facilitates the construction of PEGylated therapeutics with enhanced biocompatibility and controlled release profiles.

Synthesis

  • Route1
    • null|null
      361543-06-8
    • ~77%
    • In-stock
      HO-PEG13-OH|CS-0115026
      17598-96-8

    References

    • Andrus, Merritt B.; Turner, Timothy M.; Updegraff, Emily P.; Sauna, Zuben E.; Ambudkar, Suresh V. Tetrahedron Letters, 2001 , vol. 42, # 23 p. 3819 - 3822
  • Route2

    References

    • Jayasuriya, Nimal; Bosak, Stanislav; Regen, Steven L. Journal of the American Chemical Society, 1990 , vol. 112, # 15 p. 5851 - 5854
  • Route3

    References

    • Jayasuriya, Nimal; Bosak, Stanislav; Regen, Steven L. Journal of the American Chemical Society, 1990 , vol. 112, # 15 p. 5851 - 5854

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   151.22
  • LogP   -0.8298
  • H_Acceptors   14
  • H_Donors   2
  • Rotatable_Bonds   37

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