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CS-W001157 4
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D-(-)-α-Phenylglycine ethyl ester hydrochloride

  • CAS No. 17609-48-2

  • Cat. No. CS-W014884
  • Purity≥95%
  • MDL No.MFCD00052005

*For research and further manufacturing use only, not for direct human use.

D-(-)-α-Phenylglycine ethyl ester hydrochloride|CS-W014884

Structure of 17609-48-2

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General Information

  • CAS No. 17609-48-2
  • Cat. No. CS-W014884
  • Purity ≥95%
  • MDL No. MFCD00052005
  • Storage 4°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₄ClNO₂
  • Molecular Weight 215.68
  • Synonym(s) None
  • SMILES CCOC([C@H](N)C1=CC=CC=C1)=O.Cl

Description

Proligos DNA phosphoramidites lead to high-yield and high-quality oligonucleotides due to their high coupling efficiency. The deprotection step of automated oligonucleotide synthesis is integral to synthesis time and final product quality. Exocyclic amine functions are protected by a benzoyl group (dA(bz) and dC(bz)) or isobutyryl group (dG(ib))Key features of DNA phosphoramidites :Recommended cleavage and deprotection conditions are 8 hours at 55 Cor 24 hours at room temperature using concentrated ammonia solution, for standard base-protected oligonucleotidesThe high coupling efficiency of Proligos DNA phosphoramidites leads to high-yield and high-quality oligonucleotidesThe product belongs to ABI synthesizers.

Synthesis

  • Route1
    • null|null
      64-17-5
    • H-D-Phg-OH Ampicillin Impurity|CS-0229771
      875-74-1
    • ~95%
    • In-stock
      D-(-)-α-Phenylglycine ethyl ester hydrochloride|CS-W014884
      17609-48-2

    References

    • March, Taryn L.; Johnston, Martin R.; Duggan, Peter J. Organic Letters, 2012 , vol. 14, # 1 p. 182 - 185
  • Route2

    References

    • Journal of Organic Chemistry, , vol. 76, # 9 p. 3409 - 3415
  • Route3
    • null|null
      1289642-95-0
    • ~%
    • In-stock
      D-(-)-α-Phenylglycine ethyl ester hydrochloride|CS-W014884
      17609-48-2

    References

    • Journal of Organic Chemistry, , vol. 76, # 9 p. 3409 - 3415

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   1.6713
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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