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*For research and further manufacturing use only, not for direct human use.
Structure of 1762-34-1
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Abametapir is a potent, bench-stable inhibitor of cytochrome P450 enzymes, featuring a unique tricyclic core that enhances metabolic stability. This compound integrates seamlessly into drug metabolism studies and serves as a selective probe for evaluating CYP-mediated clearance pathways in preclinical development.
Abametapir serves as a potent, bench-stable inhibitor of the *C. difficile* toxin TcdB, enabling targeted disruption of bacterial pathogenesis pathways. Its structure incorporates a reactive warhead that selectively modifies cysteine residues within the toxin’s catalytic domain, facilitating irreversible inhibition. This property supports its utility in developing therapeutics for gastrointestinal infections and provides a valuable tool for probing clostridial toxin mechanisms in preclinical research.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: