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CS-W001157 4
Total: USD 88.00

4-Hydrazinylbenzonitrile

  • CAS No. 17672-27-4

  • Cat. No. CS-0157467
  • Purity≥97%
  • MDL No.MFCD02663085

*For research and further manufacturing use only, not for direct human use.

4-Hydrazinylbenzonitrile|CS-0157467

Structure of 17672-27-4

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General Information

  • CAS No. 17672-27-4
  • Cat. No. CS-0157467
  • Purity ≥97%
  • MDL No. MFCD02663085
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇N₃
  • Molecular Weight 133.15
  • Synonym(s) None
  • SMILES C1=C(C=CC(=C1)NN)C#N

Description

4-Hydrazinylbenzonitrile features a hydrazino group directly attached to a benzene ring bearing a nitrile handle, enabling direct incorporation into heterocyclic systems. This electron-rich scaffold facilitates coupling reactions under mild conditions and serves as a key building block for bioactive compounds in medicinal chemistry.

Application

4-Hydrazinylbenzonitrile serves as a versatile building block in synthetic organic chemistry, enabling the construction of diverse heterocyclic scaffolds through cyclization reactions. The hydrazine group readily participates in condensation with carbonyl or electrophilic functionalities, while the nitrile moiety offers compatibility with standard functional group transformations. Its bench-stable nature and ease of purification support reliable use in multi-step synthesis and medicinal chemistry campaigns.

Synthesis

  • Route1

    References

    • Journal of the American Chemical Society, , vol. 66, p. 1849

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H319
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   61.84
  • LogP   0.84388
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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