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Structure of 177478-49-8
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Methyl 1,2,3,4-tetrahydroquinoline-6-carboxylate features a saturated quinoline core with a strategically positioned ester group, enabling direct functionalization at the C6 position. This bench-stable scaffold integrates seamlessly into synthetic routes targeting bioactive heterocycles and pharmaceutical intermediates.
Methyl 1,2,3,4-tetrahydroquinoline-6-carboxylate serves as a versatile building block in medicinal chemistry, enabling late-stage functionalization via the electron-rich tetrahydroquinoline core. Its methyl ester group facilitates straightforward derivatization, while the saturated heterocyclic scaffold offers enhanced metabolic stability and favorable pharmacokinetic properties. The compound exhibits good bench stability and compatibility with standard coupling reactions, making it well-suited for constructing complex alkaloid-like scaffolds and bioactive molecules in drug discovery campaigns.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: