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CS-W001157 4
Total: USD 88.00

4-Nitrophenyl trifluoromethanesulfonate

  • CAS No. 17763-80-3

  • Cat. No. CS-M2922
  • Molecule weight271.17
  • Purity≥98%
  • MDL No.MFCD00192354

*For research and further manufacturing use only, not for direct human use.

4-Nitrophenyl trifluoromethanesulfonate|CS-M2922

Structure of 17763-80-3

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General Information

  • CAS No. 17763-80-3
  • Cat. No. CS-M2922
  • Purity ≥98%
  • MDL No. MFCD00192354
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄F₃NO₅S
  • Molecular Weight 271.17
  • Synonym(s) Trifluoromethanesulfonic Acid 4-Nitrophenyl Ester
  • SMILES FC(F)(S(OC1=CC=C([N+]([O-])=O)C=C1)(=O)=O)F

Description

4-Nitrophenyl trifluoromethanesulfonate serves as a highly effective triflating agent, leveraging the electron-deficient nitroaryl group to enhance leaving group stability. This bench-stable reagent facilitates efficient O- and N-triflation under mild conditions, enabling rapid functionalization in synthetic organic chemistry workflows.

Synthesis

  • Route1
    • null|null
      100-02-7
    • null|null
      358-23-6
    • ~96%
    • In-stock
      4-Nitrophenyl trifluoromethanesulfonate|CS-M2922
      17763-80-3

    References

    • Tetrahedron, , vol. 45, # 21 p. 6679 - 6682
  • Route2
    • null|null
      100-02-7
    • null|null
      407-25-0
    • ~81%
    • In-stock
      4-Nitrophenyl trifluoromethanesulfonate|CS-M2922
      17763-80-3

    References

    • Journal of the American Chemical Society, , vol. 123, # 36 p. 8864 - 8865
  • Route3
    • null|null
      1493-13-6
    • In-stock
      4-Nitrobenzenediazonium tetrafluoroborate|CS-0452650
      456-27-9
    • ~85%
    • In-stock
      4-Nitrophenyl trifluoromethanesulfonate|CS-M2922
      17763-80-3

    References

    • Chemistry Letters, , # 3 p. 459 - 460

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   86.51
  • LogP   1.8232
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   3

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