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Structure of 177743-06-5
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3-Chloro-2-ethoxypyridine features a pyridine core functionalized with chlorine at the 3-position and ethoxy at the 2-position, enabling selective coupling reactions. This electron-deficient heterocycle integrates readily into pharmaceutical intermediates and agrochemical scaffolds under standard conditions. The ethoxy group enhances solubility and modulates reactivity in transition metal-catalyzed transformations.
3-Chloro-2-ethoxypyridine serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its reactive chloropyridine functionality. The ethoxy group enhances solubility and modulates electronic properties, while the molecule exhibits bench stability and facilitates straightforward purification. It functions effectively in Suzuki-Miyaura, Negishi, and Buchwald-Hartwig coupling protocols, supporting efficient construction of biologically relevant scaffolds and functionalized pyridine derivatives.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: