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Structure of 1780187-45-2
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4-Bromo-5-fluoro-2-methoxybenzoic acid features a strategically positioned bromo and fluoro substituent on a methoxy-substituted benzoic acid scaffold, enabling selective functionalization in synthetic routes. This electron-deficient aromatic core integrates readily into pharmaceutical intermediates and advanced materials, offering enhanced reactivity under standard coupling conditions.
4-Bromo-5-fluoro-2-methoxybenzoic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-substituted aryl core enables efficient palladium-catalyzed cross-coupling reactions, while the carboxylic acid functionality facilitates direct derivatization or salt formation. The bromo and fluoro groups offer complementary reactivity for sequential functionalization, and the methoxy group provides moderate stability under standard reaction conditions. This compound is bench-stable, readily purified by recrystallization, and compatible with common synthetic workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: